Chryseobacterium indologenes previously classified as flavobacterium indologenes is a gram. Chryseobacterium indologenes meningitis in a healthy newborn. We report here a case of chryseobacterium meningosepticum bacteremia in a diabetic nephropathy patient on hemodialysis. It can colonize hospital environment due to ability to survive in chlorinetreated water supplies. Elizabethkingia meningoseptica international journal of infection. Chryseobacterium meningosepticum journal of clinical microbiology. Antimicrobial susceptibility and epidemiology of a. A case of healthcare associated pneumonia caused by. Describe the general characteristics of the organisms discussed in this chapter. Limited data are available on chryseobacterium spp.
Ceftizoxime is a newer third generation cephalosporin and flavobacferium been used in the therapy of gram positive menibgosepticum negative meningitis sunset appearance of eyes was present. Chryseobacterium meningosepticum, formerly known as flavobacterium meningosepticum, has been reported to cause outbreaks of meningitis, primarily in premature newborns and infants in neonatal intensive care units icu. Pdf chryseobacterium meningosepticum bacteremia in diabetic. Chryseobacterium flavobacterium meningosepticum a betalactam buster. Chryseobacterium species are chemoorganotrophic, rod shape gramnegative bacteria. Chryseobacterium indologenes is nonmotile, oxidase, and indole positive gramnegative aerobic bacilli which is widely found in plants, soil, foodstuffs, and water. Clinical and microbiological analysis of bloodstream infections caused by chryseobacterium meningosepticum in nonneonatal patients. Flavobacterium meningosepticum from neonatal meningitis. Chrysobacterium meningosepticum 20041001 ahc media. Chryseobacterium meningosepticum is a gramnegative rod with a worldwide distribution. Endocarditis due to chryseobacterium meningosepticum k bomb, a arora, n trehan abstract chryseobacterium meningosepticum is a gram negative rod widely distributed in nature. A chryseobacterium meningosepticum colonization outbreak.
Clinical and microbiological analysis of bloodstream infections. Identify the normal habitat and the routes of transmission for the organisms. Susceptibilities of chryseobacterium indologenes and. Pdf the chryseobacterium species are inhabitants of soil and water. In summary, cefepime was more active than cefpirome against the c. Conversely, onehalf of the isolates from the respiratory tract were c. Chryseobacterium flavobacterium meningosepticum a beta. Chryseobacterium and related genera consist of bacteria previously classified in the. Elizabethkingia meningoseptica is a gramnegative, rodshaped bacterium widely distributed in nature e. A chryseobacterium meningosepticum outbreak observed in 3 clusters involving both neonatal and nonneonatal pediatric patients. Incision and drainage was done and pus was sent for culture and. The taxonomic positions of six strains including the type strain of chryseobacterium meningosepticum king 1959 vandamme et al. Both cefepime and cefpirome had poor activity against c. Chryseobacterium indologenes is an uncommon human pathogen.
Chapter 24 chryseobacterium, sphingobacterium, and similar organisms objectives 1. Chryseobacterium meningoseptcium formerly called flavobacterium meningosepticum and cdc group iia is the most pathogenic member of the genus. List the appropriate media for cultivation of the organisms listed, particularly e. We report for the first time a case of community acquired chryseobacterium indologenes soft tissue infection in an immunocompetent patient. Fifty isolates 24 chryseobacterium meningosepticum, 20 chryseobacterium indologenes, two chryseobacterium gleum, and 4 chryseobacterium spp. Fifty isolates 24 chryseobacterium meningosepticum, 20 chryseobacterium indologenes, two. Endocarditis due to chryseobacterium meningosepticum bomb. Chryseobacterium meningosepticum is a ubiquitous gramnegative bacillus historically associated primarily with meningitis in neonates and a wide variety of. The pathogen causes meningitis in premature and newborn infants and pneumonia, endocarditis, postoperative bacteremia, and meningitis usually associated with severe underlying illness in adults 47. First isolation and characterization of chryseobacterium.
Although this bacterium only rarely causes human disease, it is sometimes found in food and water sources, usually in hospitals as a nosocomial transinfection. Although she received intravenous antibiotics with good in vitro activity against the organism, the. We present the case of a patient with endstage renal disease who developed purulent pericarditis with c. Phylogenetic analysis, based on 16s rrna gene sequencing, showed that the strains represent a separate. Chryseobacterium indologenes infection in a newborn.
Chryseobacterium meningosepticum bacteremia in diabetic. Atypical chryseobacterium meningosepticum and meningitis. Chryseobacterium meningosepticum infection and cardiac. Hendaus, khalid zahraldin department of pediatrics, hamad medical corporation, doha, qatar 3050. Flavobacterium meningosepticum, cdc group iia bacteriology a bacterium of soil, water, plants, foods, hospital waterincubators, tap water, hemodialysis systems, pharmaceuticals mode of transmission uncertain, but probably linked to contaminated medical devices and fluids. Chryseobacteria can also colonize patients via contaminated medical devices such as respirators, intubation tubes.
This retrospective study investigated the risk factors for mortality in patients with c. Chryseobacterium is a genus of gramnegative bacteria. Elizabethkingia meningoseptica an overview sciencedirect topics. Host factors are the major determinants of the outcomes of c. King who isolated kingella kingae in 1960 was studying. It is widely distributed in the environment, yet also an acknowledged opportunistic human pathogen. Infection is typically from an environmental source.
Chryseobacterium and elizabethkingia species may be long, thin, slightly curved, and occasionally filamentous on gram stain. Waterborne elizabethkingia meningoseptica in adult. Elizabethkingia meningoseptica formerly flavobacterium meningosepticum and, during 19942005 chryseobacterium meningosepticum is a gramnegative nonfermenting obligate aerobe. Chryseobacterium meningosepticum formerly known as flavobacterium meningosepticum or cdciia is a gramnegative rod widely. King at the communicable disease center now the centers for disease control and prevention in 1959. Chryseobacterium and acinetobacter flashcards quizlet. The ability of elizabethkingia meningoseptica isolate ch2b from freshwater tilapia oreochromis. Chryseobacterium meningosepticum is a lactosenonfermenting gramnegative bacilli ubiquitously found in the natural and hospital environment.
The genus was previously classified as flavobacterium and then reclassified in 1994 as chryseobacterium before receiving its current taxonomic designation in 2005. Formerly flavobacterium indologenes, chryserobacterium indologenes is a yellow pigmented, gramnegative filamentous, nonmotile rod and can be found in soil, plants, foodstuffs and water sources including those found in hospitals 1234. Dsm 2800 elizabethkingia meningoseptica king 1959 kim et al. A 54yearold woman who underwent continuous ambulatory peritoneal dialysis for 8 years developed peritonitis due to c. Only six species of chryseobacterium have been isolated from clinical specimens 3. We present the case of a patient with endstage renal disease who developed purulent pericarditis with c meningosepticum infection. Pdf a chryseobacterium meningosepticum outbreak observed. Chryseobacterium meningosepticum is rarely encountered as a pathogen causing peritonitis in adults. Adult infections are usually acquired nosocomially. Elizabethkingia meningosepticumon 5% sheep blood agar medium colonies 1mm in diam.
The pathogen causes meningitis in premature and newborn infants and pneumonia, endocarditis, postoperative bacteremia, and meningitis usually associated with severe underlying illness in. The genera chryseobacterium and elizabethkingia springerlink. The progressive improvement in laboratory studies is shown in table. Chryseobacterium meningosepticum as a cause of cellulitis. Their ability to exist as biofilm structures has been alluded to but not extensively investigated. Some species of chryseobacterium have been involved in human infections, acting as sporadic but. Most frequently associated with neonatal meningitis 3,4, the organism also has been described in osteomyelitis. Biofilm formation and adherence characteristics of an. Chryseobacterium, sphingobacterium, and similar organisms.
Pdf elizabethkingia meningosepticum chryseobacterium. Flavobacterium meningosepticum affects the nervous system olson et al. Members the genus chryseobacterium are widely distributed microorganisms that can be recovered from a wide variety of environments, such as fresh water, sewage and wastewater, soil or food sources, such as milk, poultry and meat and dairy products. Chryseobacterium meningosepticum, formerly known as flavobacterium meningosepticum and cdc iia, is a gramnegative rod widely distributed in nature. This pdf is available for free download from a site hosted by medknow publications. Chryseobacterium gleum holmes, owen, steigerwalt and brenner 1984b vandamme, bernardet. Elizabethkingia meningoseptica, formerly chryseobacterium meningosepticum, is the most important pathogen, particularly in neonatal meningitis. The genbankemblddbj accession numbers for the 16s rrna gene sequences of elizabethkingia meningoseptica atcc 253t and. View enhanced pdf access article on wiley online library html view download pdf for offline viewing. Elizabethkingia species were first described by elizabeth o. Case reportendocarditis due to chryseobacterium meningosepticum.
It is known to cause meningitis in neonates and premature infants. Chryseobacterium form typical yelloworange color colonies due to flexirubintype pigment. Chryseobacterium indologenes, a possible emergent organism. Request pdf chryseobacterium in burn wounds chryseobacteria are gram negative organisms, formerly known as flavobacteria, which rarely cause infections of. For reasons that are explained in the section phylogeny, the splitting of the genus chryseobacterium was proposed very recently kim et al. The genus contains more than 100 described species from diverse habitats, including freshwater sources, soil, marine fish, and. Gram stain of agar isolates reveals long, thin rods that can. Elizabethkingia meningoseptica, previously known as chryseobacterium meningosepticum, is a gramnegative bacillus that is widely distributed in nature. Chryseobacterium meningosepticum is a gram negative rod widely distributed in nature. It is a wellknown agent of meningitis in premature and newborn infants.
Chryseobacterium indologenes an overview sciencedirect. Outbreaks usually extend over a period of a few weeks 15, 16, although they may last longer 14, 17, and this was the case in the present study. Emerging chryseobacterium indologenes infection in. Chryseobacterium meningosepticum is a ubiquitous gramnegative bacillus historically associated with meningitis in premature neonates. Clinical infection caused by c meningosepticum is very rare among healthy adults. Unforeseeable presentation of chryseobacterium indologenes. A 11 year female child, from southasia of indian origin presented with fever, pain and swelling in right leg for 3 days with no significant past history. Chryseobacterium flavobacterium meningosepticum, an organism resistant to multiple antibiotics, is an occassional cause of infection in immunocompromised adults and in neonates, in whom it most commonly causes meningitis. Successful control of elizabethkingia meningoseptica outbreak.
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