Waterborne elizabethkingia meningoseptica in adult. Elizabethkingia meningoseptica, formerly chryseobacterium meningosepticum, is the most important pathogen, particularly in neonatal meningitis. Infection is typically from an environmental source. Chryseobacterium indologenes meningitis in a healthy. Susceptibilities of chryseobacterium indologenes and. Chryseobacterium flavobacterium meningosepticum a betalactam buster. Clinical infection caused by c meningosepticum is very rare among healthy adults. In summary, cefepime was more active than cefpirome against the c. The pathogen causes meningitis in premature and newborn infants and pneumonia, endocarditis, postoperative bacteremia, and meningitis usually associated with severe underlying illness in adults 47. A case of healthcare associated pneumonia caused by. Chryseobacterium, sphingobacterium, and similar organisms.
Chryseobacterium meningosepticum formerly known as flavobacterium meningosepticum or cdciia is a gramnegative rod widely. Most frequently associated with neonatal meningitis 3,4, the organism also has been described in osteomyelitis. The progressive improvement in laboratory studies is shown in table. Adult infections are usually acquired nosocomially. For reasons that are explained in the section phylogeny, the splitting of the genus chryseobacterium was proposed very recently kim et al. Phylogenetic analysis, based on 16s rrna gene sequencing, showed that the strains represent a separate. Emerging chryseobacterium indologenes infection in. We report for the first time a case of community acquired chryseobacterium indologenes soft tissue infection in an immunocompetent patient. Elizabethkingia meningoseptica is a gramnegative, rodshaped bacterium widely distributed in nature e. It is widely distributed in the environment, yet also an acknowledged opportunistic human pathogen. Both cefepime and cefpirome had poor activity against c.
Chryseobacterium meningosepticum journal of clinical microbiology. Chryseobacterium form typical yelloworange color colonies due to flexirubintype pigment. Dsm 2800 elizabethkingia meningoseptica king 1959 kim et al. View enhanced pdf access article on wiley online library html view download pdf for offline viewing. Pdf chryseobacterium meningosepticum bacteremia in diabetic. Atypical chryseobacterium meningosepticum and meningitis. Gram stain of agar isolates reveals long, thin rods that can. Elizabethkingia meningoseptica international journal of infection. Chryseobacterium indologenes is an uncommon human pathogen.
Fifty isolates 24 chryseobacterium meningosepticum, 20 chryseobacterium indologenes, two. Members the genus chryseobacterium are widely distributed microorganisms that can be recovered from a wide variety of environments, such as fresh water, sewage and wastewater, soil or food sources, such as milk, poultry and meat and dairy products. Endocarditis due to chryseobacterium meningosepticum bomb. Elizabethkingia meningoseptica, previously known as chryseobacterium meningosepticum, is a gramnegative bacillus that is widely distributed in nature.
Conversely, onehalf of the isolates from the respiratory tract were c. The ability of elizabethkingia meningoseptica isolate ch2b from freshwater tilapia oreochromis. Elizabethkingia meningoseptica an overview sciencedirect topics. Case reportendocarditis due to chryseobacterium meningosepticum. Chryseobacterium meningoseptcium formerly called flavobacterium meningosepticum and cdc group iia is the most pathogenic member of the genus. First isolation and characterization of chryseobacterium. Outbreaks usually extend over a period of a few weeks 15, 16, although they may last longer 14, 17, and this was the case in the present study. Identify the normal habitat and the routes of transmission for the organisms. Biofilm formation and adherence characteristics of an. Chryseobacterium and related genera consist of bacteria previously classified in the.
Chryseobacteria can also colonize patients via contaminated medical devices such as respirators, intubation tubes. This pdf is available for free download from a site hosted by medknow publications. King who isolated kingella kingae in 1960 was studying. Unforeseeable presentation of chryseobacterium indologenes. Pdf the chryseobacterium species are inhabitants of soil and water. A chryseobacterium meningosepticum outbreak observed in 3 clusters involving both neonatal and nonneonatal pediatric patients. A 11 year female child, from southasia of indian origin presented with fever, pain and swelling in right leg for 3 days with no significant past history. Chryseobacterium indologenes meningitis in a healthy newborn. Describe the general characteristics of the organisms discussed in this chapter. Chryseobacterium meningosepticum, formerly known as flavobacterium meningosepticum and cdc iia, is a gramnegative rod widely distributed in nature. Chryseobacterium indologenes an overview sciencedirect. Elizabethkingia meningoseptica formerly flavobacterium meningosepticum and, during 19942005 chryseobacterium meningosepticum is a gramnegative nonfermenting obligate aerobe. Chryseobacterium meningosepticum is a gram negative rod widely distributed in nature. Chryseobacterium meningosepticum is rarely encountered as a pathogen causing peritonitis in adults.
Chryseobacterium indologenes previously classified as flavobacterium indologenes is a gram. Their ability to exist as biofilm structures has been alluded to but not extensively investigated. We present the case of a patient with endstage renal disease who developed purulent pericarditis with c. The genus contains more than 100 described species from diverse habitats, including freshwater sources, soil, marine fish, and.
Flavobacterium meningosepticum affects the nervous system olson et al. Only six species of chryseobacterium have been isolated from clinical specimens 3. Antimicrobial susceptibility and epidemiology of a. The genbankemblddbj accession numbers for the 16s rrna gene sequences of elizabethkingia meningoseptica atcc 253t and. Chryseobacterium meningosepticum, formerly known as flavobacterium meningosepticum, has been reported to cause outbreaks of meningitis, primarily in premature newborns and infants in neonatal intensive care units icu. Formerly flavobacterium indologenes, chryserobacterium indologenes is a yellow pigmented, gramnegative filamentous, nonmotile rod and can be found in soil, plants, foodstuffs and water sources including those found in hospitals 1234. Chryseobacterium indologenes, a possible emergent organism. Chryseobacterium is a genus of gramnegative bacteria. Pdf elizabethkingia meningosepticum chryseobacterium. This retrospective study investigated the risk factors for mortality in patients with c. It is known to cause meningitis in neonates and premature infants.
Ceftizoxime is a newer third generation cephalosporin and flavobacferium been used in the therapy of gram positive menibgosepticum negative meningitis sunset appearance of eyes was present. Clinical and microbiological analysis of bloodstream infections caused by chryseobacterium meningosepticum in nonneonatal patients. List the appropriate media for cultivation of the organisms listed, particularly e. Chrysobacterium meningosepticum 20041001 ahc media. Hendaus, khalid zahraldin department of pediatrics, hamad medical corporation, doha, qatar 3050.
Elizabethkingia meningosepticumon 5% sheep blood agar medium colonies 1mm in diam. Chryseobacterium flavobacterium meningosepticum a beta. Fifty isolates 24 chryseobacterium meningosepticum, 20 chryseobacterium indologenes, two chryseobacterium gleum, and 4 chryseobacterium spp. Chryseobacterium meningosepticum is a ubiquitous gramnegative bacillus historically associated with meningitis in premature neonates. Limited data are available on chryseobacterium spp. The genera chryseobacterium and elizabethkingia springerlink. Pdf a chryseobacterium meningosepticum outbreak observed.
Flavobacterium meningosepticum from neonatal meningitis. Flavobacterium meningosepticum, cdc group iia bacteriology a bacterium of soil, water, plants, foods, hospital waterincubators, tap water, hemodialysis systems, pharmaceuticals mode of transmission uncertain, but probably linked to contaminated medical devices and fluids. We report here a case of chryseobacterium meningosepticum bacteremia in a diabetic nephropathy patient on hemodialysis. Chryseobacterium flavobacterium meningosepticum, an organism resistant to multiple antibiotics, is an occassional cause of infection in immunocompromised adults and in neonates, in whom it most commonly causes meningitis. A 54yearold woman who underwent continuous ambulatory peritoneal dialysis for 8 years developed peritonitis due to c.
Chryseobacterium meningosepticum is a ubiquitous gramnegative bacillus historically associated primarily with meningitis in neonates and a wide variety of. Chryseobacterium indologenes infection in a newborn. Chryseobacterium species are chemoorganotrophic, rod shape gramnegative bacteria. Chryseobacterium gleum holmes, owen, steigerwalt and brenner 1984b vandamme, bernardet. Chryseobacterium indologenes is nonmotile, oxidase, and indole positive gramnegative aerobic bacilli which is widely found in plants, soil, foodstuffs, and water. Although this bacterium only rarely causes human disease, it is sometimes found in food and water sources, usually in hospitals as a nosocomial transinfection. Chryseobacterium meningosepticum infection and cardiac.
We present the case of a patient with endstage renal disease who developed purulent pericarditis with c meningosepticum infection. It can colonize hospital environment due to ability to survive in chlorinetreated water supplies. Chryseobacterium meningosepticum is a gramnegative rod with a worldwide distribution. The taxonomic positions of six strains including the type strain of chryseobacterium meningosepticum king 1959 vandamme et al. Clinical and microbiological analysis of bloodstream infections. Chryseobacterium and acinetobacter flashcards quizlet. King at the communicable disease center now the centers for disease control and prevention in 1959. Chryseobacterium meningosepticum bacteremia in diabetic. The pathogen causes meningitis in premature and newborn infants and pneumonia, endocarditis, postoperative bacteremia, and meningitis usually associated with severe underlying illness in. Some species of chryseobacterium have been involved in human infections, acting as sporadic but. Successful control of elizabethkingia meningoseptica outbreak.
Elizabethkingia species were first described by elizabeth o. Although she received intravenous antibiotics with good in vitro activity against the organism, the. Chryseobacterium meningosepticum as a cause of cellulitis. A chryseobacterium meningosepticum colonization outbreak. Request pdf chryseobacterium in burn wounds chryseobacteria are gram negative organisms, formerly known as flavobacteria, which rarely cause infections of. Chryseobacterium and elizabethkingia species may be long, thin, slightly curved, and occasionally filamentous on gram stain. Host factors are the major determinants of the outcomes of c. Endocarditis due to chryseobacterium meningosepticum k bomb, a arora, n trehan abstract chryseobacterium meningosepticum is a gram negative rod widely distributed in nature. It is a wellknown agent of meningitis in premature and newborn infants.
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